100 books like The Social Life of DNA

Only dogged research could unearth the story of how one Black woman’s death – and the harvesting of her cells – could change the course of medical research.

It is a story of how some innocuous biological matter could grow into a hothouse of excess. Pharma companies enriched themselves reproducing the cells of Henrietta Lacks but did little or nothing for the family who lost their matriarch.  

For me, this book unleashed the idea of shaping deep research into a story can change our view of society.

It is hard to believe that Matt Ridley’s grand tour of the human genome was published back in 1999. Yet even today, more than two decades later, Ridley’s engaging, chromosome by chromosome investigation of our genetic make-up remains a marvel that has never been equaled. From the genes that enable the most basic chemical processes in our cells to those that determine our height and eye color, the mysterious “junk DNA” that lives between our genes, and speculation about the ways that genes affect personality, behavior, and society, Ridley brings science to life in this engaging and timeless book.

More than thirty years ago, when I was conducting research on the psychology of altruism and moral development, a biologist recommended that I read The Selfish Gene. 

Reading Dawkins’ book caused me to change my theoretical orientation completely.  It enabled me to see that if I wanted to understand altruism and morality, I needed to understand how the genes that guide the construction of the mental mechanisms that cause us to help others evolved. 

Although the title of the book implies that we are selfish by nature, the contents explain how selfish genes can guide the development of unselfish animals.  

This book is less about who we are than how we relate to nature. It is important for all of us to be reminded periodically that humans are only actors in a much larger and more powerful environment that operates beyond our control. Many books have been written in the past 50 years about the next pandemic, and David Quammen’s account of how diseases spread from animals to humans is one of the best. For me, it puts the daily feed of political bickering and distant violence in a refreshing perspective, mixed with a level of invigorating nervousness. 

Experiences with HIV and SARS should have taught us how vulnerable we are to new diseases. The 2014-2016 Ebola outbreak in West Africa, which killed over 14,000 people, demonstrated how irrational and self-destructive we can behave when fear takes grip. Why, then, were we so unprepared, either medically or psychologically, to face… show more.

I think I’m on my third or fourth copy of this book, because I keep giving it away! This is an absolutely stunning, gorgeously illustrated book about the spacesuits worn by Buzz Aldrin and Neil Armstrong during the moon landing. The bid to design the suits was won by the Playtex Corporation—the lingerie company!—over a bunch of industrial materials suppliers, because Playtex knew how to design for the body in ways the other firms didn’t. The book is organized into twenty-one chapters, in homage to the twenty-one layers of the spacesuit, and it’s a thing of beauty. It weaves together the history of aeronautics, the politics of the Space Race, technology design, and mid-century fashion so seamlessly, and makes you think about each of these topics differently.

Everyone who knows me has at some point had to hear me recount at least one anecdote from this book! Dundes was a professor of folklore, and this book is about all the ways Orthodox Jews navigate the prohibitions of the Sabbath. It includes a lot of incredible history about how technology plays a role in helping people do what they need to do without technically breaking the rules—like the Shabbat elevator in the title, which stops automatically at every floor in a building so that observant Jews don’t have to press a button to operate the elevator (which is prohibited). This book changed how I think about automation, and it’s so richly and respectfully written. One of my all-time favorites.

A book about pencil-and-paper baseball scorekeeping might seem like an odd one to include on a list about technology! But that’s precisely the point: even though by-hand scoring seems like an unnecessary relic in the digital age, this book so beautifully explains why people do it anyway, and how much richness and storytelling and personality there can be in a practice that, at first glance, seems like it might just be rote transcription. Recording data isn’t a science—it can be an art, a tradition, and a joy unto itself.

My copy of this book has so many dog-eared pages and “!”s scrawled in the margins that it’s almost ridiculous. This is the story of how, in the 1960s, New York City and the RAND Corporation used algorithmic modeling to decide where to locate fire stations in the city. It was pretty much a disaster: because of the choices the modelers made about what to measure and how to measure it, they ended up cutting services to many of the poorest neighborhoods in NYC. Joe Flood is a journalist, and it shows—this book is stunning in how it combines the stories of human beings with crystal-clear accounts of the technical decisions made by the computing “whiz kids.”

This might not look like a big data book but, for me, the race to read the human genome marks the birth of big data in biology, in the form of a tsunami of DNA sequencing data. I edited Craig Venter’s A Life Decoded, the first genetic autobiography, which explored the implications of becoming the first person to gaze upon all six billion ‘letters’ of their own genetic code. While working on Craig’s extraordinary story I came across The Genome War and thought James Shreeve did a brilliant job in describing the drama, rivalry, and personalities in the race to sequence the very first human genomes between government-backed scientists and Celera, Craig’s company.

The new science of DNA reveals a lot about how we think about identity.

Humans are a migratory species and our stories are complicated. Ancient DNA don't always match people's stories about their ancestors. Rather than being in a place for thousands of years, sometimes we replaced those who were there before or only the males of the group.

Sometimes we completely replaced the group that was there before but the original group's culture persisted or even replaced the invading culture. The book complicates our understanding of indigeneity and belonging.